Anxiety, Stress & Sleep
Dual-mushroom synergy for balanced calm & rest.
This introductory blend combines the adaptogenic depth of Reishi with the sleep-enhancing, GABAergic effects of Amanita muscaria. Bioactivated with Cellisome® technology, this balanced pairing delivers a steady foundation of calm during the day while gently supporting smoother sleep onset at night.*
Each bottle contains 1 gram of Reishi and 1 gram of Amanita muscaria ultrasonic crystalized extracts, offering a synergistic daily baseline for stress resilience, mood balance, and relaxation.*
- Calms stress while enhancing sleep onset*
- Supports emotional steadiness & recovery*
- Establishes a daily foundation for nervous-system balance*
- Certified Organic • 100% Fruiting Bodies • Alcohol-Free
- Free US shipping over $60 · International shipping
Reishi:
- Promotes deep calm and emotional balance*
- Supports restorative sleep quality and duration*
- Helps regulate stress hormones and reduce daily tension*
Amanita Muscaria:
- Promotes calm and nervous system relaxation*
- Supports dream vividness and recall*
- Eases physical and mental tension for deeper rest*
- Cellisome® Bioactivated Reishi Crystals (1G)
- Proprietary Organic Phospholipid Blend
- Cellisome® Bioactivated Amanita Muscaria Crystals (1G)
- Proprietary Organic Phospholipid Blend
Clean formulation:
- Certified Organic (excluding Amanita)
- Naturally sweetened with glycerin
- Gluten-Free
- Third-Party Tested
- 100% Mushroom Fruiting Bodies
Take one dropper of each (1mL) sublingually once daily. Hold under tongue for 30 seconds, then swallow.
- Best used on an empty stomach or between meals
- Do not mix with hot liquids
- Consistency builds results – take daily
- Reishi (Ganoderma lucidum) may lower blood pressure or blood sugar; use with caution if taking antihypertensive or antidiabetic medications. Avoid during pregnancy or breastfeeding.
- Amanita muscaria may cause drowsiness, dizziness, or nausea. Avoid combining with alcohol or sedatives (e.g., benzodiazepines, sleep aids). Not recommended during pregnancy or breastfeeding, and not for children.
General: Start low to assess sensitivity. Do not combine with alcohol or cannabis. Discontinue and consult a professional if any adverse effects occur.
Ultra-Potent Crystallized Extracts
Microvora’s Cellisome® Bioactivated process delivers maximum bioactive content in a fast-acting, highly absorbable form.
“I didn’t expect the combo to feel this balanced. Amanita on its own makes my nights softer, and Reishi helps me stay level during the day, but together it feels like my whole system finally stopped fighting itself. I feel calmer without getting sluggish, and my focus comes online faster in the morning. I didn’t change anything else in my routine, yet my mood swings feel less sharp and I’m not carrying the same background tension. It’s been a surprisingly steady shift, and I’m sticking with it."
- Marilyn F.
Benefits You Can See and Feel*
Total
calm
Deep, Dream-
Rich Sleep
Stress
Harmony
Body
Unwind
Mood
Steady
Mind-Body
Synergy
Recovery
Rhythm
Ease +
Clarity
How Amanita + Reishi Shapes Neural Dynamics
Neural activity is governed by the interplay between inhibitory interneuron systems, excitatory pyramidal-cell networks, and state-regulation circuits linking the cortex, thalamus, hippocampus, and cerebellum. In combination, Amanita and Reishi engage these systems through a broader set of bioactives: muscimol and related GABAergic ligands influence chloride conductance in inhibitory circuits, while Reishi triterpenes, nucleosides, and β-glucans interact with pathways connected to HPA-axis signaling, autonomic tone, and immune–brain communication. Together, these inputs adjust membrane polarization, oscillatory frequency bands, and cross-regional synchrony, shaping how the brain filters incoming signals, coordinates internal network activity, and transitions between higher-arousal and lower-arousal states.
Calming alkaloids like muscimol act on GABA-A receptors, easing neural overactivity and supporting restorative sleep depth.
Ibotenic acid (and its detox products) modulate glutamatergic tone, balancing excitatory drive with inhibitory calm.
Rare amino acids like ergothioneine and glutathione (GSH) buffer oxidative stress in neurons and mitochondria.
Adenosine, guanosine, inosine calm excitatory firing, promote parasympathetic tone, and support healthy sleep cycles.
Reishi triterpenes (ganoderic acids, lucidenic acids) modulate the HPA axis, reduce cortisol reactivity, and support immune resilience.
Reishi up-levels SOD, catalase, GPx, GST and glutathione with PQQ, vitamins C/E, melatonin & allies to buffer oxidative stress.*
β-glucans and glycoproteins prime innate immunity and stabilize neuroimmune balance.
Mushroom sterols (ergosterol, β-sitosterol, lanosterol) support cell membrane integrity and vitamin D2 conversion.
Chlorogenic, caffeic, ferulic, gallic acids offer neuroprotective and anti-inflammatory effects.
GABA, taurine, tryptophan, phenylalanine regulate neurotransmission and improve stress adaptation.
We love questions
Have more questions? Visit our Help Center or inquire at hello@microvora.com
Microvora’s Reishi + Amanita crystallized extracts deliver a calm, restorative reset for both mind and body. Reishi’s triterpenes and beta-glucans help balance the stress response (HPA axis), smooth out nightly wake-ups, and support deeper, more continuous sleep. Amanita’s muscimol gently modulates GABA-A pathways to ease nervous tension, quiet mental noise, and enhance dream quality. Together, they promote steadier mood, parasympathetic calm, and a more fully restorative night—so you wake genuinely recharged.*
Place one full dropper (1 ml) under your tongue and hold for 30–60 seconds before swallowing. Sublingual uptake is fast—many feel a noticeable exhale within minutes. For sleep support, use in the evening; for daytime calm, start with a reduced amount and adjust as needed.*
Yes—pair by goal and time of day. These combos come from our other formulas and play nicely with Reishi + Amanita:
- Hair growth, skin glow & collagen support: Tremella + Chaga — hydration and antioxidant support for skin elasticity and a healthier scalp environment.*
- Energy burnout & adrenal recovery: Cordyceps + Chaga — sustained daytime energy with antioxidant support for stress-heavy periods.*
- Immune harmony & gut-skin glow: Turkey Tail + Tremella — prebiotic beta-glucans for balanced immune tone plus deep hydration for a clearer, more resilient complexion.*
- Daytime steadiness & focus (lighter use): Low Amanita + Lion’s Mane; add Cordyceps on demanding days.*
Yes. Every batch is made with certified organic fruiting bodies only – no fillers, grains or allergens.
No. We use a glycerin + distilled water base – completely alcohol-free and shelf-table. Nothing artificial. Just pure, potent crystallized Reishi + Amanita.